Bristol City look certain to be without Cole Skuse, who has been struggling with a persistent toe injury.
He will be joined on the sidelines by Jamal Campbell-Ryce, after the winger damaged his hamstring against Swansea.
MATCH PREVIEW
Phil Brown goes into his fifth game as Preston manager still looking for his first win since taking over at Deepdale. His team are without a victory in six matches and are three points adrift at the bottom of the table.
Millen accepts Preston expectations
One of Brown's priorities has been to tighten up a defence that has conceded 49 league goals this season.?Two of them came in Tuesday's defeat at Barnsley, where their shortcomings at the back were evident once again.
City have also been struggling of late. The Robins are only three places and five points above the relegation zone, and are looking for a first win in six Championship games.
Quite simply, the goals have dried up for Keith Millen's side. They have not scored in five matches and have completed six hours of league football without finding the net.
MATCH FACTS
Head-to-head
• Preston have won three and drawn two of their last five home games against City, who last won at Deepdale in December 1996.
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• These clubs have scored 99 league goals against each other.
Preston
• Preston have lost five of their last seven matches.
• They have won only five of 27 Championship matches, and lost 16 of them.
• North End have dropped 21 points this season from winning positions.
• Striker Nathan Ellington is set for his 400th career league appearance, while Wayne Brown could make his 350th.
Bristol City
• City have won only one of their last 10 matches.
• They have drawn two and lost four of their last six away league games.
• Former England goalkeeper David James is set to make his 850th club career appearance, while Marvin Elliott is in line for his 250th career league start.
Source: BBC Sport
Source: BBC Sport