Bristol City will be without goalkeeper Dean Gerken, who looks certain to miss the rest of the season with a suspected broken collarbone.
Young Irishman Stephen Henderson is expected to take Gerken's place.
MATCH PREVIEW
Prior to the Easter weekend, Sheffield Wednesday manager Alan Irvine targeted at least two more wins to preserve their Championship status.
Saturday's draw at QPR - their fifth in six games - kept Wednesday two points above the relegation zone, but Irvine knows his side need a victory to calm the nerves.
That will not come easily against a Bristol City side rejuvenated under caretaker manager Keith Millen. Saturday's creditable draw against Nottingham Forest extended City's unbeaten record to four matches under him since the departure of Gary Johnson.
That run has guaranteed them another season of Championship football. However, Millen will not tolerate any City slackers and has challenged his players to eclipse last year's points tally of 61.
MATCH FACTS
Head-to-head
• Bristol City are unbeaten in the last six meetings between these clubs, although the most recent three have all been drawn.
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Sheffield Wednesday
• Wednesday have not lost in six matches (W1, D5).
• They have failed to score in an unequalled 16 Championship games.
• Wednesday are the only club not to have had a player sent off in a Championship game this season.
• On-loan forward Luke Varney is one goal short of 50 in his league career.
Bristol City
• Three of Bristol City's four away wins have been against current bottom-half clubs.
• The Robins have conceded 11 goals in the last five minutes of Championship games this season, more than any other club.
• Bradley Orr is poised to make his 200th league start for Bristol City.
• Jamal Campbell-Ryce could play on the eve of his 27th birthday.
MOST RECENT MEETING
Bristol City 1-1 Sheff Wed (31 October 2009)
Bristol City scorer: Maynard 59.
Sheffield Wednesday scorer: Varney 75.
Source: BBC Sport
Source: BBC Sport